is the result of an individuals’ deepest beliefs being challenged or revealed as false, and their consequent failure to adapt. So those beliefs first need to be ascertained.
A new evolutionary development? You could argue that the crucible of late capitalism is perfoming this experiment upon western society as we speak.
The systematic derangment of an individual is, I think, faciliated by knowing them, the more depth of knowledge the easier it would be to unseat their balance.
Foucault. “Madness is silenced by Reason.”
mania 